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Can't sleep? Stop sedating, start targeting.

Why knocking yourself out often misses the problem, and the three pathways I'd look at instead.

“If you're struggling to sleep like me, taking a bunch of things that just sedate you might be targeting the wrong problem”

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Three pathways

  • Daridorexant (orexin): “This is personally one of my favorite sleep medications I've ever used, if not my favorite.”
  • Clonidine (noradrenaline): “the most notable if you're on a bunch of stimulants and androgens”, for “that fight or flight, wired but tired feeling”.
  • L-THP (dopaminergic drive).